Professor,Division of Life Science& Health
AssociateDean, Graduate School at Shenzhen, Tsinghua University
Shenzhen518055, P. R. China
Phone:(86)-755-26033033
Fax:(86)-755-26033033
E-mail:malan@sz.tsinghua.edu.cn
EDUCATION
Ph.D.in Stem Cell Biology, August 2003, University of Chinese Academy of Sciences,Beijing, China
M.S.in Immunology, June 1993, Peking University, Beijing, China
B.S.in Genetics, July 1987, Wuhan University, Wuhan, China
PROFESSIONAL EXPERIENCE
2014-present Associate Dean, Graduate School at Shenzhen,Tsinghua University
2013-2014 Director, Research Office, Graduate Schoolat Shenzhen, Tsinghua University
2012-presentLaboratory Chief, Shenzhen Innovative Nano-Diagnostic Reagents EngineeringLaboratory
2011-present Professor, Graduate School atShenzhen, Tsinghua University
2005-2011 Associate professor, Graduate School atShenzhen, Tsinghua University
1997-1998Visiting Scholar, Wisconsin National Primate Research Center, University ofWisconsin-Madison
2000-2005Associate Professor, School of Life Sciences, Yunnan University
1995-2000 Lecturer, School of Life Sciences, YunnanUniversity
1993-1995 Teaching Assistant, School of Life Sciences,Yunnan University
1987-1990Assistant Scientist, Kunming Institute of Zoology, The Chinese Academy ofSciences
AWARDSAND HONORS
2006 China Standard Innovation Award，StandardizationAdministration of China
2004 National innovation expert, China Federationof Trade Unions
2003 2003 'China Economic Women of the Year,China Women's Federation
2002 New century women's outstanding inventor,China Women's Federation and China Intellectual Property Office
2002 National 'three eight' red bannerpacesetter, China Women's Federation
TEACHING
80450142：Molecular Immunology
60450014：Modern Life Science& Biotechnology Experiment
86000221：Cancer Diagnostics andNanomedicine
RESEARCH INTERESTS
1.STEM CELL BIOLOGY
2.NANO-BIOMEDICINE
3.VACCINE & ANTIBODY BIO-ENGINEERING
FINISHEDPROJECTS（As PI）
[1]“New nano-assay technology for the HIV rapid diagnosis”, Hi-Tech Research and Development Program ofChina, From Dec. 2006 to Nov. 2010.
[2]“Development of new fluorescent immunoassay for the simultaneous detection ofthe residues of four varied veterinary drugs”, Shenzhen Science and TechnologyInnovation Council Grant, from Oct. 2008 to Dec. 2010.
[3]“Development of high sensitive fluorescent immunoassay for the detection of theresidues of drugs in the foods”, Shenzhen Science and Technology Innovation Council Grant, from Jan. 2009to Dec. 2010.
ONGOING PROJECTS（As PI）
[1]“Integrated study of quantum dot-based nano-material and its application fordiagnosis of major diseases”, Hi-TechResearch and Development Program of China, From Sep. 2013 to Sep. 2016.
[2]“Shenzhen innovative nano-diagnostic reagents engineering laboratory”, Shenzhen Development and Reform CommissionGrant, from Dec. 2012 to Dec. 2014.
[3]“Development of sensitive distinguishable POCT reagents for the detection ofinfluenza A (H1N1) virus”, GuangdongScience and Technology Council Grant, from Oct. 2012 to Sep. 2014.
[4]“Development of a fluorescent quantum dots-based sensitive reagent for rapidquantitative detection of procalcitonin (PCT)”, Shenzhen Science and Technology Innovation Council Grant, from Jan. 2013to Jan. 2014.
[5]“Development of the fluorescent immuno-reagent for early detection of gastriccancer ”, Shenzhen Science andTechnology Innovation Council Grant, from Aug. 2014 to Aug. 2016.
[6]“Research & Development of sensitive POCT immunoassay kits for thedetection of highly pathogenic avian influenza virus”, Shenzhen Science andTechnology Innovation Council Grant, from Oct. 2014 to Oct. 2016.
SELECTED PUBLICATIONS
[1]Feng Wu, Hang Yuan, Changhua Zhou, Mao Mao, Qian Liu, Huaibin Shen, Yu Cen,Zhifeng Qin, Ling Song Li* , Lan Ma*. Multiplexed detection of influenza Avirus subtype H5 and H9 via quantum DoT-based immunoassay. Biosensors andBioelectronic,, http://dx.doi.org/10.1016/j.bios.2015.10.002
[2]Wenxiu Zhao, Lei Jin, Hang Yuan, Zhiyang Tan, Changhua Zhou, Lin Song Li*&Lan Ma*. Targeting human embryonic stem cellswith quantum dot-conjugatedphages. SCIENTIFIC REPORTS（2013）, 3 : 3134, DOI: 10.1038/srep03134.
[3]Changhua Zhou, Mao Mao, Hang Yuan, HuaibinShen, FengWu ,Lan Ma* , Lin Song Li*.Fluorescent QDs-polystyrene composite nanospheres for highly efficient andrapid protein antigen detection, J Nanopart Res (2013) 15:1901
[4]Zhou Changhua; Yuan Hang; Wang Xin; Shen Huaibin; Guo Yi; Xu Li; Wu Feng; MaLan*; LiLin Song*. CdSe/ZnS Quantum Dots with Multi-Shell Protection: Synthesisand Application in the Detection of Ractopamine Residue in Swine Urine, Scienceof Advanced Materials, Volume 5, Number 3, March 2013 , pp. 285-294(10).
[5]Sujuan Wang; Changhua Zhou; Hang Yuan; Huaibin Shen; Wenxiu Zhao; Lan Ma*; LinSong Li*. A robust ligand exchange approach for preparing hydrophilic,biocompatible photoluminescent quantum dots. Materials Research Bulletin 48(2013) 2836–2842.
[6]Dan Liu, Feng Wu, Changhua Zhou, Huaibing Shen, Hang Yuan, Zuliang Du, Lan Ma∗, Lin Song Li∗. Multiplexed immunoassaybiosensor for the detection of serum biomarkers －β-HCG and AFP of Down Syndrome based onphoto luminescent water-soluble CdSe/ZnS quantum dots, Sensors and Actuators B186 (2013) 235–243.
[7]Weiwei Xu, Jinzhong Niu, Hangying Shang,Huaibin Shen*, Lan Ma*, Lin Song Li. Facile synthesis of AgAu alloy andcore/shell nanocrystalsby using Ag nanocrystals as seeds, Gold Bull (2013)46:19–23.
[8]WenxiuZhao , Xiang Ji , Fangfang Zhang , Liang Li and Lan Ma*. Embryonic Stem Cell Markers.Molecules 2012, 17, 6196-6236; doi:10.3390/molecules17066196
[9]Huaibin Shen, Hang Yuan, Feng Wu, Xianwei Bai, Changhua Zhou, Hongzhe Wang,Tikang Lu, Zhifeng Qin, Lan Ma* and LinSong Li*. Facile synthesis of high-quality CuInZnxS2+x core/shell nanocrystalsand their application for detection of C-reactive protein. J. Mater. Chem.,2012, 22, 18623–18630.
[10]Huaibin Shen,Hongzhe,Wang,Hang Yuan, Lan Ma* and Lin Song Li*. Size-, shape-,and assembly-controlled synthesis of Cu2xSe nanocrystals via a non-injectionphosphine-free colloidal method. CrystEngComm, 2012, 14, 555–560.
[11]WeiweiXu, Huaibin Shen, Jin Zhong Niu, Changhua Zhou, Cailan Yu,Xiaomin Li,Yuan Hang, Hongzhe Wang, Lan Ma* and Lin Song Li*. Facile synthesis andobservation of discontinuous red-shift photoluminescence of CdTe/CdS core/shellnanocrystals. CrystEngComm, 2012, 14, 272–277.
[12]Xu, Shasha; Shen, Huaibin; Zhou, Changhua; Hang, Yuan; Liu, Changsong; Wang,Hongzhe; Ma, Lan*, Li, Lin Song*. Effect of Shell Thickness on the OpticalProperties in CdSe/CdS/Zn0.5Cd0.5S/ZnS and CdSe/CdS/ZnxCd1-xS/ZnSCore/Multishell Nanocrystals. J. Phys. Chem. C 2011, 115, 20876–20881.
[13]Changhua Zhou,Hang Yuan, Huaibin Shen, Yi Guo, Xiaomin Li, Dan Liu, Li Xu, LanMa* and Lin Song Li*. Synthesis of size-tunable photoluminescent aqueousCdSe/ZnS microspheres via a phase transfer method with amphiphilic oligomer andtheir application for detection of HCG antigen, J. Mater. Chem., 2011, 21,7393–7400.
[14]Huaibin Shen, HongzheWangChanghuaZhou,Jin Zhong Niu, Hang Yuan, Lan Ma* and LinSong Li*. Large scale synthesis of stable tricolor Zn1 - xCdxSe core/multishellnanocrystals via a facile phosphine-free colloidal method, Dalton Trans., 2011, 40, 9180-9188.
[15]Huaibin Shen, HangYuan, Jin Zhong Niu, Shasha Xu, ChanghuaZhou, LanMa* and LinSong Li*. Phosphine-free synthesis of high-quality reverse type-I ZnSe/CdSecore with CdS/CdxZn1−xS/ZnSmultishell nanocrystals and their application for detection of human hepatitisB surface antigen, Nanotechnology., 2011,22, 375602 (10pp).
[16]Xiaomin Li, Honglei Si, Jinzhong Niu, Huaibin Shen, Changhua Zhou, Hang Yuan,Hongzhe Wang, Lan Ma* and Lin Song Li*. Size-controlled syntheses andhydrophilic surface modification of Fe3O4, Ag, and Fe3O4/Ag heterodimernanocrystals，Dalton Trans., 2010, 39, 10984–10989.
AFFILIATIONSAND ACTIVITIES
2007-present Member, Nano Science and Technology Branchof Chinese Society of Micro-Nano Technology
2014-present Vice president, Shenzhen Society of LifeScience and Biological Association
2014-present Full affiliate member，Houston MethodistResearch Institute (HMRI)
