Research area: Biofabrication, Regenerative medicine, Point-of-care diagnosis
Research expertise:
1. Microfluidics
2. 3D bioprinting
3. Tissue engineering
4. Biomaterials

Description of research:
Professor Shaohua Ma has interests mainly in the interface of science and engineering, by innovating engineering techniques, including microfluidics, 3D bioprinting and micro-/nano-fabrications, towards translational developments in precision and regenerative medicine. Research focuses include fabrication of in vitro tissue / organ models for drug development, organ repair and organ transplantation, organ-on-a-chip, early detection of circulating tumour cells by using microfluidics, etc.

Courses to be offered: Introduction to mechanobiology, 32 credit hours

Education background:
2013，UK，University of Cambridge，Department of Chemistry，PhD
2010，UK，University of Cambridge，Department of Chemistry，MPhil
2009，China，Sun Yat-sen University， Department of Polymer Materials and Engineering, BEng

Professional experiences:
2013-2017，UK，University of Oxford，Department of Chemistry，Postdoctoral research associate
2012-2013，UK，University College London，Department of Mechanical Engineering，Research associate

Publications:

[1] Haoran Zhao, Zitian Wang, Shengwei Jiang, Jiaqi Wang, Zhiwei Hu, Peter E. Lobie, Shaohua Ma*, Microfluidics synthesis of injectable angiogenic microgels, Cell Reports Physical Science, 2020, 100047.

[2]   Yong Wang, Mengqi Ji, Shengwei Jiang, Xukang Wang, Jiamin Wu, Jintao Fan, Shaohua Ma*, Lu Fang*, Qionghai Dai*, Augmenting vascular disease diagnosis by vasculature-aware unsupervised learning, Nature Machine Intelligence, 2020, in press.

[3]   Edgar Palan, Xukang Wang, Wilhelm Huck, Qionghai Dai, Shaohua Ma*, Intelligent microfluidics: Machine learning-driven applications in materials science and biomedicine, Matter, under review.

[4]   Yuanxiong Cao, Haoran Zhao, Shaohua Ma*, Cascade pumping overcomes hydraulic resistance and moderates shear conditions for slow gelatin fiber shaping in narrow tubes, iScience, 2020, in press.

[5]   Xinlong Pang, Haoran Zhao, Shaohua Ma*, A microfluidics reaction system for a multi- component reaction with automation and high chemoselectivity, Advanced Intelligent Systems, 2020, 2, 1900191.

[6]   Chengyong He*, Fengkai Ruan, Shengwei Jiang, Jie Zeng, Hanying Yin, Yongxing Zhang, Chonggang Wang, Shaohua Ma*, Zhenghong Zuo*, Black Phosphorus Quantum Dots Causes Renal Organoid Dysfunction, Small, 2020, 2001371.

[7]   Swati Kaushik, Sonu Gandhi, Mehak Chauhan, Shaohua Ma, Souvik Das, Deepa Ghosh, Aneesh Chandrasekharan, Md Bayazeed Alam, Avanish Singh Parmar, Alpana Sharma*, T. R. Santhoshkumar*, Deepa Suhag*, Water-Templated, Polysaccharide-rich Bioartificial 3D Microarchitectures as Extra-Cellular Matrix Bioautomatons, ACS Appl. Mater. Interfaces, 2020, 12, 18, 20912-20921.

[8] Shaohua Ma*, Microfluidics tubing as a synthesizer for ordered microgel networks, Soft Matter, 2019, 15, 3848 – 3853.

[9] Shaohua Ma*, N. Mukherjee, E. Mikhailova, H. Bayley, Gel microrods for 3D tissue printing, Advanced Biosystems, 2017, 1700075.

[10] Shaohua Ma*, N. Mukherjee, Microfluidics fabrication of soft microtissues and bottom-up assembly, Advanced Biosystems, 2018, 1800119.

[11] Shaohua Ma*, Engineering inverse opals with enclosed voids via bottom-up assembly of double emulsions, Chemical Engineering Science, 2019, 205, 414-419.

[12] Shaohua Ma, S. Balabani, W. T. S. Huck, Double emulsion deformation under conditions of flow cytometry sheath focusing, Lab on a Chip, 2015, 15, 4291-4301.

[13] Shaohua Ma, J. Sherwood, W. T. S. Huck, S. Balabani, The microenvironment of double emulsions in rectangular microchannels, Lab on a Chip, 2015, 15, 2327-2334.

[14] Shaohua Ma, J. Sherwood, W. T. S. Huck, S. Balabani, On the flow topology inside droplets moving in rectangular microchannels, Lab on a Chip, 2014, 14, 3611-3620.

[15] J. Thiele, Y. Ma, S. M. C. Bruekers, Shaohua Ma, W. T. S. Huck, Designer hydrogels for cell cultures: A materials selection guide, Advanced Materials, 2014, 26, 125-148.

[16] Shaohua Ma, M. Natoli, X. Liu, M. P. Neubauer, F. M. Watt, A. Fery, W. T. S. Huck, Monodisperse collagen-gelatin beads as potential platforms for 3D cell culturing, Journal of Materials Chemistry B 2013, 1, 5128-5136.

[17] Shaohua Ma, J. Thiele, X. Liu, Y. Bai, C. Abell, W. T. S. Huck, Fabrication of Microgel Particles with Complex Shapes via Selective Polymerization of Aqueous Two-Phase System, Small 2012, 8, 2356 – 2360.

[18] Shaohua Ma, Gelatin-based microfluidics device with the feature sizes smaller than 100 μm for the production of oil-in-water emulsions, Microfluidics and Nanofluidics, 2019, 23, 35.

[19] J. Thiele, V. Chokkalingam, Shaohua Ma, D. A. Wilson, W. T. S. Huck, Vesicle budding from polymersome templated by microfluidically prepared double emulsions, Materials Horizons 2014, 1, 96-101.

Patents:
1. H. Bayley, S. Ma, PCT/G B2017/051598, pending.

Laboratory recruitment:
The laboratory always recruits postdoctors and research assistants with backgrounds in engineering, chemistry and biology (such as stem cells, iPSCs and Cancer research).