Medical Systems Biology Research Center
Department of Biomedical Engineering
Tsinghua University School of Medicine
Haidian District, Beijing 100084
Jing Cheng, PhD, is a Cheung Kong Professor at Medical Systems Biology Research Center, Department of Biomedical Engineering, Tsinghua University School of Medicine, Director of National Engineering Research Center for Beijing Biochip Technology，Member of the Chinese Academy of Engineering.
Dr. Cheng received his B.Eng. degree in Electrical Engineering from Tongji University (China) and PhD degree in Forensic Sciences from the University of Strathclyde (UK). His experience includes 8 years as an Electrical Engineer at Ziyang Internal Combustion Locomotive Factory (China) and as a Lecturer in Forensic Sciences at Southwest University of Political Science and Law (China). He also gained additional postdoctoral experience at the University of Strathclyde and the University of Aberdeen (UK) and University of Pennsylvania (USA) where he was appointed as a Research Assistant Professor in the School of Medicine. In 1996 he joined Nanogen Inc in San Diego as a Staff Scientist /Engineer where he was later promoted to Principal Scientist and Engineer, and Principal Investigator. From 1999 to 2001 he assumed the role of Chief Technology Officer at Aviva Biosciences Corp in San Diego, USA. From 2000 to present, he is managing the over-all research as the director of National Engineering Research Center for Beijing Biochip Technology.
Dr. Cheng developed the world’s first system of laboratory-on-a-chip in 1998 and the work was featured in the front cover story of the June 1998 issue of Nature Biotechnology, also cited in the breakthrough of the year by Science in the same year. He was awarded Nanogen's most prestigious award NanoGrant in 1999, National Young Scientist Award in 2004, Qiushi Outstanding Youth Technology Transfer Award in 2004, Second Prize of the National Awards for Technological Innovation in 2007, Ho Leung Ho Lee Prize for Scientific and Technological Innovation in 2008, Tanjiazhen Life Science Innovation Award in 2008, 1st China Western-Return Scholar Entrepreneur “Tengfei” Award in 2010 and Second Prize of Beijing Invention Patents in 2011, Chinese Academy of Engineering Guanghua Award of Engineering Science and Technology, the China National Outstanding Engineer Award and the National Outstanding Scientific and Technological Workers in 2014. Dr. Cheng has published 123 peer-reviewed papers and edited 8 books. In addition, he has obtained 42 European and US patents. He has been an invited speaker to many international conferences.
His current interest is in the development of biochip-based microsystems and ultra-high throughput drug screening systems.
1. Cheng, J.Biochips for Translational Medicine. Science, Selected Presentations from the 2011 Sino-American Symposium on Clinical and Translational Medicine, S. Sanders Ed. (Science/AAAS, Washington, DC, 2011): 68.
2. Qin, W., Dong, P., Ma, C., Mitchelson, K., Deng, T., Zhang, L., Sun, Y., Feng, X., Ding, Y., Lu, X., He, J., Wen, H. and Cheng, J. MicroRNA-133b is a key promoter of cervical carcinoma development through the activation of the ERK and AKT1 pathways. Oncogene, 2012, 31, 4067–4075.
3. Guo, H., Liu, H., Mitchelson, K., Rao, H., Luo, M., Xie, L., Sun, Y., Zhang, L., Lu, Y., Liu, R., Ren, A., Liu, S., Zhou, S., Zhu, J., Zhou, Y., Huang, A., Wei, L., Guo, Y. and Cheng, J. MicroRNAs-372/373 promote the expression of hepatitis B virus through the targeting of nuclear factor I/B. Hepetology, 2011, 54 (3): 808–819.
4. Xie, L., Ma, R., Han, C., Su, K., Zhang, Q., Qiu, T., Wang, L., Huang, G., Qiao, J., Wang, J. and Cheng, J. Integration of sperm motility and chemotaxis screening with a microchannel-based device. Clinical Chemistry,2010, 56(8): 1270-1278.
5. Wang, L., Zhu, J., Deng C., Xing W. and Cheng, J.An automatic and quantitative on-chip cell migration assay using self-assembled monolayers combined with real-time cellular impedance sensing. Lab on a Chip, 2008, 8(6): 872-878. (Cover)
6. Li, C., Pan, Q., Guo, Y., Li, Y., Gao, H., Zhang, D., Hu, H., Xing, W., Mitchelson, K., Xia, K., Dai, P. and Cheng, J.Construction of a multiplex allele-specific PCR-based universal array (ASPUA) and its application to hearing loss screening. Human Mutation, 2008, 29(2): 306-314.
7. Qiao, J., Shao, W., Wei, H., Sun, Y., Zhao, Y., Xing, W., Zhang, L., Mitchelson, K. and Cheng, J. Novel high-throughput profiling of human transcription factors and its use for systematic pathway mapping. Journal of Proteome Research, 2008, 7(7): 2769-2779.
8. Shi, L., Reid, L.H., Jones, W.D., Shippy, R., Warrington, J.A., Baker, S.C., Collins, P.J., de Longueville, F., Kawasaki, E.S., Lee, K.Y., Luo, Y., Sun, Y.A., Willey, J.C., Setterquist, R.A., Fischer, G.M., Tong, W., Dragan, Y.P., Dix, D.J., Frueh, F.W., Goodsaid, F.M., Herman, D., Jensen, R.V., Johnson, C.D., Lobenhofer, E.K., Puri, R.K., Scherf, U., Thierry-Mieg, J., Wang, C., Wilson, M., Wolber, P.K., Zhang, L., Amur, S., Bao, W., Barbacioru, C.C., Lucas, A.B., Bertholet, V., Boysen, C., Bromley, B., Brown, D., Brunner, A., Canales, R., Cao, X.M., Cebula, T.A., Chen, J.J., Cheng, J., et al.
9. The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements. Nature Biotechnology, 2006, 24(9): 1151-1161.
Connell, J.P.Preparation and hybridization analysis of DNA/RNA from E. coli on microfabricated bioelectronic chips. Nature Biotechnology, 1998, 16(6): 541-546. (Cover)¢10. Cheng, J., Sheldon, E.L., Wu, L., Uribe, A., Gerrue, L.O., Carrino J., Heller, M.J., Carrino, J. and O
11. Cheng,J. and Kricka, L.J. (eds.) Biochip Technology.Harwood Academic Publishers, Pennsylvania, U.S.A.,2001.